Effect of propionate on the production of natamycin with Streptomyces gilvosporeus XM-172

  • K Jing
  • X Hao
  • Y Lu
Keywords: Precursor, propionate, natamycin production, Streptomyces gilvosporeus XM-172.

Abstract

This study described the influence of feeding short-chain fatty acids and alcohols on natamycin production in the glucose basal medium, produced by Streptomyces gilvosporeus XM-172. The highest natamycin production was obtained with feeding propionate as compared to other precursors. The optimal propionate concentration and feeding time were 6 g L-1 and early log phase, respectively. This optimal propionate feeding strategy led to a natamycin production of 6.72 g L-1, which was nearly 85% higher than that of the control. It was firstly revealed that propionate could greatly promote natamycin biosynthesis by S. gilvosporeus.

Key words: Precursor, propionate, natamycin production, Streptomyces gilvosporeus XM-172.

Published
2013-10-28
Section
Articles

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eISSN: 1684-5315