PROMOTING ACCESS TO AFRICAN RESEARCH

African Journal of Environmental Science and Technology

Log in or Register to get access to full text downloads.

Remember me or Register



Studies on the hepatic antioxidant defense system in λ cyhalothrin-induced oxidative stress in fresh water tilapia (Oreochromis mossambicus)

R Parthasarathy, J Joseph

Abstract


The present study was undertaken to determine the effects of λ cyhalothrin-induced oxidative stress in fresh water tilapia (Oreochromis mossambicus) with respect to changes in the levels of lipid peroxidation [LPO], reduced glutathione [GSH], glutathione-dependent antioxidant enzymes (glutathione peroxidase [GPX] and glutathione-S-transferase [GST]) and antiperoxidative enzymes (catalase [CAT] and superoxide dismutase [SOD]). Significant (P<0.05) elevation in the level of lipid peroxidation was observed in λ cyhalothrin-intoxicated fishes as compared to controls. A concomitant (P<0.05) decline in hepatic antioxidant status was also observed. The results of the present investigation have indicated that the tissue antioxidant defense system is operating at a lower rate despite increased λ cyhalothrin-induced oxidative stress.

Key words: Antioxidant status, λ cyhalothrin, lipid peroxidation, Oreochromis mossambicus, oxidative stress, synthetic pyrethroid.




AJOL African Journals Online