Fibroblastic rheumatism: Scientific Letter

Abstract

Fibroblastic Rheumatism (FR) is a rare rheumatologic entity of unknown etiology. The pathophysiological mechanism involving fibroblast proliferation is characterized by symmetrical polyarthritis associated with sudden onset of cutaneous nodules, flexion contractures. Bone erosion can occur as the disease progresses and destructive arthropathy is inconstant. The diagnosis of fibroblastic rheumatism is based on histological study of the nodules. Fibroblastic rheumatism treatment is di cult and relies on corticosteroids or immunosuppressive treatment. Given its rarity, we considered necessary to present the diagnostic and therapeutic approach to this disease still imperfectly known.

Keywords: Fibroblastic rheumatism, Sclerodactyly, Nodules, Corticosteroids