Primary antiphospholipid syndrome with multiple organ involvement: case report

Abstract

Antiphospholipid syndrome is a systemic autoimmune disease, characterized by the occurrence of venous and arterial thrombosis, and the detection of circulating antiphospholipid antibodies. Thrombosis mainly affect the deep veins and cerebral circulation, but can also occur in other sites such as visceral arteries, cerebral venous sinuses, and micro vessels in the lungs, heart and eyes. This is a case of a 32 year old African male with AntiPhospholipid Syndrome (APS) presenting with multiple organ involvement-left central retinal artery occlusion, right MCA infarct, superior mesenteric artery thrombosis with multiple splenic infarcts, and severe aortic regurgitation with heart failure.