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Antimalarial activity of <i>Mammea Africana</i>
Abstract
The antimalarial activity of ethanolic stembark extract of Mammea africana was studied in vivo in mice infected with Plasmodium bergheiduring early and established infections. Mammea africana extract(30 – 90mg/kg/day) exhibited a significant (P<0.05) blood schizontocidal activity both in 4-day early infection and in established infection with a significant mean survival time comparable to that of the standard drug,chloroquine, 5mg/kg/day.The stembark extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.
African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006:43-49
African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006:43-49
