Antimalarial activity of Mammea Africana

  • Jude E Okokon
  • Aniekan E Udokpoh
  • Grace A Essiet

Abstract

The antimalarial activity of ethanolic stembark extract of Mammea africana was studied in vivo in mice infected with Plasmodium bergheiduring early and established infections. Mammea africana extract(30 – 90mg/kg/day) exhibited a significant (P<0.05) blood schizontocidal activity both in 4-day early infection and in established infection with a significant mean survival time comparable to that of the standard drug,chloroquine, 5mg/kg/day.The stembark extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.

African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006:43-49
Published
2006-10-04
Section
Articles

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eISSN: 0189-6016