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Analysis on 113 cases of adverse reactions caused by β-lactam antibiotics

J Lu
C Cai
Y Gu
Y Tang
J Xue
K Huang


The objectives of this study were to learn about the characteristics and rules of the occurrence of adverse reactions caused by lactam antibiotics and provide a  reference for clinical drug use.

Methods: A retrospective study was made to analyse the 113 case reports of adverse reactions caused by â-lactam antibiotics collected in our hospital between 2007 and 2009.

Results: 113 cases of ADR involved 17 kinds of â-lactam antibiotics,  headed by ceftriaxone sodium. The most common manifestation was skin and accessory damage; nervous system and gastrointestinal system damage were also easier to find, and the administration route was mainly intravenous infusion. Conclusion: The clinical application of â-lactam antibiotics should pay attention to adverse reaction monitoring and rational drug use to reduce the incidence of adverse reactions.

Key words: adverse drug reactions; â-lactam antibiotics

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eISSN: 0189-6016