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SYNTHESIS OF CYCLOBUTANE ANALOGUES


Yan Bai Yin
Zhan Qian Song
Zong De Wang
Shi Bin Shang
Zhao Sheng Cai

Abstract

2-(3-Acetyl-2,2-dimethylcyclobutyl)acetic acid (pinonic acid) was synthesized using α-pinene as raw material and potassium permanganate as oxidant. This compound reacted with substituted aniline to produce eight kinds of derivatives with cyclobutane moiety. The yields of the cyclobutane analogues ranged from 24.9 to 78.2 %.

KEY WORDS: Cyclobutane analogues, Pinonic acid, Oxidation


Bull. Chem. Soc. Ethiop. 2009, 23(1), 135-139.

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eISSN: 1726-801X
print ISSN: 1011-3924