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Regioselective iodination of aryl amines using 1,4-dibenzyl-1,4-diazoniabicyclo [2.2.2] octane dichloroiodate in solution and under solvent-free conditions


M. Alikarami
S. Nazarzadeh
M. Soleiman-Beigi

Abstract

1,4-Dibenzyl-1,4-diazoniabicyclo[2.2.2]octane dichloroiodate is an efficient and regioselective reagent for iodination of aryl amines. A wide variety of aryl amines in reaction with this reagent afforded regioselectively iodinated products. The iodination reaction can be carried out in solution or under solvent-free condition at room temperature.

 

KEY WORDS:  Regioselective iodination, Aryl amines, 1,4-Dibenzyl-1,4-diazoniabicyclo [2.2.2] octane dichloroiodate,  Solvent-free conditions

 

Bull. Chem. Soc. Ethiop. 2015, 29(1), 157-162

DOI: http://dx.doi.org/10.4314/bcse.v29i1.15