Microwave-assisted synthesis of some nitro-benzimidazoles and their salicyl and isatin Schiff bases
A series of 5-nitrosubstituted benzimidazole and 6-nitro substituted benzimidazole derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o-phenylenediamine under microwave irradiation. The structure of newly synthesized compounds was confirmed by IR, 1H-NMR, 13C-NMR, LC-MS spectroscopy and elemental analysis.
KEY WORDS: Benzimidazole, Isatin, Salicyl aldehyde, Iminoester hydrochloride, Microwave irradiation
Bull. Chem. Soc. Ethiop. 2017, 31(2), 351-359.