Synthesis of new nano Schiff base complexes: X-ray crystallography, thermal, electrochemical and anticancer studies of nano uranyl Schiff base complexes

  • F. D. Firuzabadi
  • Z. Asadi
  • R. Yousefi
Keywords: Uranyl Schiff base complex, Anticancer activities, Thermal studies, Electrochemistry, X-ray crystallography

Abstract

This study presents synthesis and characterization of new nano uranyl Schiff base complexes. Electrochemistry of these complexes showed a quasireversible redox reaction without any successive reactions. Furthermore, X-ray crystallography exhibited that beside the coordination of tetradentate Schiff base, one solvent molecule (dimethylformamide) was also coordinated. According to Coats-Redfern plots the kinetics of thermal decomposition of the studied complexes was first-order in all stages. Anticancer activities of the uranyl Schiff base complexes against cancer cell lines (Jurkat) was studied and determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide) assay. The results demonstrated that the complexes with aliphatic bridging units showed less anticancer activities than those having the aromatic units.

               

KEY WORDS: Uranyl Schiff base complex, Anticancer activities, Thermal studies, Electrochemistry; X-ray crystallography

 

Bull. Chem. Soc. Ethiop. 2018, 32(1), 89-100

DOI: https://dx.doi.org/10.4314/bcse.v32i1.8

Published
2018-04-12
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924