ANTIPARASITIC PRENYLATED ISOFLAVONOIDS FROM SEEDS OF MILLETTIA GRIFFONIANA

  • Dieudonne Ngamga<sup>a</sup> <sup>a</sup>Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon
  • Emmanuel Yankep<sup>b</sup> <sup>b</sup>Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon
  • Pierre Tane<sup>a</sup> <sup>a</sup>Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon
  • Merhatibeb Bezabih<sup>c</sup> <sup>c</sup>Department of Chemistry, Faculty of Science, University of Botswana, P.O. Box UB00704, Gaborone, Botswana
  • Bonaventure T. Ngadjui<sup>b</sup> <sup>b</sup>Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon
  • Z. Tanee Fomum<sup>b</sup> <sup>b</sup>Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon
  • Berhanu M. Abegaz<sup>c</sup>* <sup>c</sup>Department of Chemistry, Faculty of Science, University of Botswana, P.O. Box UB00704, Gaborone, Botswana
Keywords: Millettia griffoniana, Fabaceae, Papilionoideae, Isoflavones, Trypanocidal, Anti-plasmodial

Abstract

Two new prenylated isoflavonoids, namely 7-methoxyebenosin and griffonianone E along with the known calopogonium isoflavone B and 7,2\'-dimethoxy-4\',5\'-methylenedioxy isoflavone were isolated from the seeds of Millettia griffoniana. Their structures were assigned on the basis of spectroscopic data. The new compounds exhibit moderate trypanocidal and anti-plasmodial activities.

KEY WORDS: Millettia griffoniana, Fabaceae, Papilionoideae, Isoflavones, Trypanocidal, Anti-plasmodial

Bull. Chem. Soc. Ethiop. 2005, 19(1), 75-80.
Published
2005-07-20
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924