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Bulletin of the Chemical Society of Ethiopia

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ANTIPARASITIC PRENYLATED ISOFLAVONOIDS FROM SEEDS OF MILLETTIA GRIFFONIANA

Dieudonne Ngamga<sup>a</sup> , Emmanuel Yankep<sup>b</sup> , Pierre Tane<sup>a</sup> , Merhatibeb Bezabih<sup>c</sup> , Bonaventure T. Ngadjui<sup>b</sup>, Z. Tanee Fomum<sup>b</sup>, Berhanu M. Abegaz<sup>c</sup>*

Abstract


Two new prenylated isoflavonoids, namely 7-methoxyebenosin and griffonianone E along with the known calopogonium isoflavone B and 7,2\'-dimethoxy-4\',5\'-methylenedioxy isoflavone were isolated from the seeds of Millettia griffoniana. Their structures were assigned on the basis of spectroscopic data. The new compounds exhibit moderate trypanocidal and anti-plasmodial activities.



KEY WORDS: Millettia griffoniana, Fabaceae, Papilionoideae, Isoflavones, Trypanocidal, Anti-plasmodial


Bull. Chem. Soc. Ethiop. 2005, 19(1), 75-80.



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