SIGMOISIDE E: A NEW ANTIBACTERIAL TRITERPENOID SAPONIN FROM ERYTHRINA SIGMOIDEA (HUA)

  • J. Kouam
  • X. Siewe Noundou Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Cameroon
  • Laure B. Kouitcheu Mabeku Microbiology Laboratory, Department of Biochemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon
  • A. Meli Lannang Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Cameroon
  • M. Iqbal Choudhary H.E.J. Research Institute of Chemistry, International Centre of Chemical Sciences, University of Karachi-75270, Pakistan
  • Z.T. Fomum Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P. O. Box 812, Cameroon
DOI: 10.4314/bcse.v21i3.21218
Keywords: <i>Erythrina sigmoidea</i>, Stem bark, Triterpenoid, Saponin, Isoflavone, Leguminoseae

Abstract

Chemical analysis of the stem bark of Erythrina sigmoidea (Leguminoseae) yielded two known isoflavones, 6,8-diprenylgenisteine (3) and warangalone (4) as well as a new triterpenoid saponin designated sigmoiside E (1). Its structure was established by chemical and spectroscopic means as 16-O-β-D-galactopyranosyl maniladiol (1). Sigmoiside E exhibited antibacterial activity against gram-negative bacteria.
KEY WORDS: Erythrina sigmoidea, Stem bark, Triterpenoid, Saponin, Isoflavone, Leguminoseae

Bull. Chem. Soc. Ethiop. 2007, 21(3), 373-378.
Published
2007-11-26
Issue
Vol. 21 No. 3 (2007)
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924