EFFICIENT SODIUM SELENATE-CATALYZED SYNTHESIS OF 3,4-DIHYDRO-2(1H)-PYRIMIDINONES AND –THIONES UNDER SOLVENT-FREE CONDITIONS

  • Rahim Hekmatshoar
  • Maryam Heidari
  • Majid M. Heravi
  • Bita Baghernejad Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, Iran
Keywords: Dihydropyrimidinones, Sodium selenate, Biginelli reaction, Three component reaction

Abstract

Sodium selenate efficiently catalyzes the three-component Biginelli reaction of an aldehyde, a,β-keto ester and urea or thiourea under solvent-free conditions to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or –thiones in excellent yields.
KEY WORDS: Dihydropyrimidinones, Sodium selenate, Biginelli reaction, Three component reaction

Bull. Chem. Soc. Ethiop. 2009, 23(1), 141-144.
Published
2009-04-01
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924