Main Article Content

Synthesis and characterization of a new azo quinoline ligand and its metal complexes with spectrophotometric determination and biological efficacy study of its Hg(II) complex

Esraa Rasool Radhi
Fatema Jabbar Ali
Khdeeja Jabbar Ali


ABSTRACT. An azo quinoline ligand, (E)-2-((4-iodophenyl)diazenyl)-8-hydroxyquinoline (IPDHQ), was synthesized by the coupling reaction of 4-iodoaniline diazonium salt with 8-hydroxyquinoline. The synthesized ligand and its Cd(II), Pd(II), Cu(II) and Hg(II) complexes were spectrally characterized by UV‒Vis spectrophotometry, FT-IR, mass spectral analysis, 1H-NMR, magnetic sensitivity and molar conductivity. The general formula of the Cd(II), Cu(II) and Hg(II) complexes is [M(L)2].Cl2.H2O with octahedral geometry, while the general formula of the Pd(II) complex is [M(L).Cl2].H2O with square planer geometry. A simple and rapid spectrophotometric procedure was suggested for the determination of Hg(II) using the synthesized ligand as a spectrophotometric reagent. By measuring the absorbance for the resulting orange complex at 430 nm, the linearity range was 0.5-15 µg mL-1, and the interfering effect was also studied. The synthesized azo ligand and its Hg(Ⅱ) complex were tested for their biological activity against four bacterial strains.

KEY WORDS: Azo quinoline ligand, 8-Hydroxy quinoline, 4-Iodoaniline, Azo metal complexes, Spectrophotometric determination, Biological efficacy study

Bull. Chem. Soc. Ethiop. 2023, 37(6), 1459-1470. 

Journal Identifiers

eISSN: 1726-801X
print ISSN: 1011-3924