Synthesis and antibacterial activities of cyclodimers of styrene oxides

  • Ofentse Mazimba Chemistry Department, University of Botswana, Private Bag 00704, Gaborone, Botswana
  • Runner R. Majinda Chemistry Department, University of Botswana, Private Bag 00704, Gaborone, Botswana
  • Ishmael B. Masesane Chemistry Department, University of Botswana, Private Bag 00704, Gaborone, Botswana
DOI: 10.4314/bcse.v25i2.65907
Keywords: Dioxanes, Dioxolanes, Styrene, Epoxidation, Cyclodimerization, Antibacterial activities

Abstract

A simple synthetic procedure for preparation of 1,4-dioxanes or 1,3-dioxolanes from styrene oxides is described. Electron-donating groups on the aromatic ring of the styrene oxides were found to favour formation of 1,4-dioxanes while electron-withdrawing groups favoured formation of 1,3-dioxolanes. Antibacterial activities of the prepared cyclodimers are reported.

 KEY WORDS: Dioxanes, Dioxolanes, Styrene, Epoxidation, Cyclodimerization, Antibacterial activities

 

Bull. Chem. Soc. Ethiop. 2011, 25(2), 299-304.

Published
2011-05-02
Issue
Vol. 25 No. 2 (2011)
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924