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Synthesis and antibacterial activities of cyclodimers of styrene oxides


Ofentse Mazimba
Runner R. Majinda
Ishmael B. Masesane

Abstract

A simple synthetic procedure for preparation of 1,4-dioxanes or 1,3-dioxolanes from styrene oxides is described. Electron-donating groups on the aromatic ring of the styrene oxides were found to favour formation of 1,4-dioxanes while electron-withdrawing groups favoured formation of 1,3-dioxolanes. Antibacterial activities of the prepared cyclodimers are reported.

 KEY WORDS: Dioxanes, Dioxolanes, Styrene, Epoxidation, Cyclodimerization, Antibacterial activities

 

Bull. Chem. Soc. Ethiop. 2011, 25(2), 299-304.


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eISSN: 1726-801X
print ISSN: 1011-3924