EFFECT OF AQUEOUS EXTRACT (CRUDE) OF LEAVES OF Vernonia Amygdalina (DEL) ON BLOOD GLUCOSE, SERUM ALBUMIN AND CHOLESTEROL LEVELS IN DIABETIC ALBINO RATS

  • FO Uhegbu Department of Biochemistry, Abia State University, Uturu
  • Kingsley J Ogbuehi Department of Biochemistry, Abia State University, Uturu
Keywords: Blood glucose, serum albumin, Cholesterol, hypoglycemic, antilipolytic and lipogenic effects

Abstract

Effect of crude aqueous extract of leaves of Vernonia amygdalina on blood glucose, serum albumin and cholesterol levels on alloxan induced diabetic albino rats was investigated. Blood glucose, serum albumin and cholesterol levels were significantly reduced. From 296.75 ± 9.0mg/dl to 179.0 ± 7.3mg/dl for blood glucose; 4.08 ± 0.4mg/dl to 0.93 ± 0.23mg/dl for serum albumin, while cholesterol level decreased from 280.33 ± 4.65mg/dl to 170.45 ± 4.52mg/dl.

The effect was dose dependent, as the reduction followed increase in dose given to the animals. The biochemical implication of our findings are discussed.

KEY WORDS: Blood glucose, serum albumin, Cholesterol, hypoglycemic, antilipolytic and lipogenic effects.

Global Jnl Pure & Applied Science Vol.10(1) 2004: 189-194
Published
2004-05-25
Section
Articles

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eISSN: 1118-0579