Primary osteosarcoma of the uterus: a report of two cases

  • Kofi Effah Department of Obstetrics & Gynaecology, Catholic Hospital, Battor, Ghana
  • Edem Hiadzi Lister Hospital & Fertility Centre, Accra, Ghana
  • Anita Osabutey Department of Obstetrics & Gynaecology, Catholic Hospital, Battor, Ghana
  • Alex K. Boateng Department of Obstetrics & Gynaecology, Catholic Hospital, Battor, Ghana
  • Agyeman B. Akosa Cellular Pathology Laboratory, Ghana Standards Authority, Accra, Ghana.
  • Jehoram T. Anim Cellular Pathology Laboratory, Ghana Standards Authority, Accra, Ghana.
Keywords: Osteosarcoma, Uterus, Primary, extraskeletal, Ghana

Abstract

Primary extraskeletal osteosarcoma is an uncommon disease and has been reported to affect the uterus only rarely. Less than 20 cases have so far been reported in the English literature. The common clinical presentation is heavy bleeding per vaginam, and in virtually all cases, the diagnosis has been made at an advanced stage of the disease. Various authors have recommended adjuvant chemotherapy, but outcomes have so far been uniformly poor, with survival extended by months rather than years. We present two cases of this rare condition, which were diagnosed four months apart within our histopathology laboratory andconfirmed the very late presentation of the disease in one and the poor survival of both patients.

Published
2021-09-30

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print ISSN: 0016-9560