Prevalence of Hepatitis B surface antigen sero-positivity and Hepatitis C virus among voluntary blood donors in Abia State University Teaching Hospital Aba, Nigeria
Hepatitis B and C viruses are among the common infectious diseases of the world and constitute a major global health burden. Consequent upon their mode of transmission, thorough screening of blood has become absolutely necessary, making quick provision of safe blood rather difficult. This study aims at determining the sero-prevalence of hepatitis B and C viruses among voluntary blood donors in our centre. This was a hospital-based cross sectional study and was carried out at the blood bank of the teaching hospital, Aba, from June 2013 and December 2014. Five hundred and thirty consecutively recruited voluntary blood donors were screened for hepatitis B and hepatitis C virus infections. Hepatitis B virus infection was screened using hepatitis B surface antigen by ELISA, while hepatitis C virus infection was screened using anti-HCV antibodies by ELISA. The biodata of the donors were obtained. The prevalence of hepatitis infection among the blood donors was 51 (9.6%). HBsAg and ant-HCV were reactive in 7.26% and 1.5% of the study population respectively while co-infection was recorded in 0.74% of the donors. In conclusion, this study confirmed the presence of viral hepatitides among voluntary blood donors and these infections can be transmitted through blood in Aba, Nigeria.
Key words: Hepatitis B, Hepatitis C, blood donors, Aba, Nigeria.