Fluorometric Assessment Of Lysosomal Enzymes In Garlic Oil Treated Diabetic Rats
AbstractThe effect of Garlic oil on Lysosomal enzymes in streptozotocin-induced diabetic rats were investigated fluorometrically. The serum lysosomal enzymes assayed include β-glucuronidase, N-acetylglucosaminidase (β-hexosaminidase) (NAG) β-D-galactosidase and α-D-galactosidase.
The results of the study in nMole-4Mu/hr/ml show that β-glucuronidase (44.3 ± 0.28), β-hexosaminidase (1615.2±35.2), β-D-galactosidase (20.6±0.70) and α-D-galactosiminidase (10.3±1.00) were significantly elevated in diabetic rats compared to normal rats β-glucuronidase (35.3±0.45), NAG (885.0±44.2), β-D-galactosidase (9.50 ± 0.10) and α-D-galactosidase (4.50±0.60). The treatment of diabetic rats with garlic oil significantly (P<0.05) reduced the observed increase in lysosomal enzymes
Key Words: Garlic oil, lysosomal enzymes mellitus
Jnl Med. Investigation & Practice Vol. 3 2001: 35-39
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Prof. Stephen Onwere
Department of Obstetrics & Gynaecology,
Abia State University Teaching Hospital,