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Phenotypic detection of various β-lactamases among multidrug resistant isolates of Escherichia coli and Klebseilla pneumoniae isolated from urinary tract infections in some Egyptian hospitals
In the present study a total of 205 isolates were recovered from186 different cases from urinary tract infections ward in some Egyptian hospitals (Dar El-Fouad Hospital, EL-Demerdash Hospital, El-Sheikh Zayed Hospital and Kasr Al-Ainy Hospital) from September 2011 to October 2012. The most predominant bacteria isolated from urine samples was Escherichia coli 49.76% (102/205), followed by Klebseilla pneumonia represented 14.63% (35/205). The growing number and rapid increase in antibiotic resistance among E. coli, Klebsiella spp. has prompted us to investigate the resistance mechanisms among these isolates. It was found that the rates of potential ESβL production among isolates of E. coli and Klebsiella spp. were 46.08% (47/102) and 60% (21/35) respectively. While, the rates of potential ESβLs and AmpC β-lactamase production among E. coli and Klebsiella spp., were 22.55% (23/102) and 25.71% (9/35), respectively. Our study revealed that the rates of carbapenemases production among E. coli and Klebsiella spp. were 0.98% (1/102) and 8.57% (3/35), respectively.