Nigerian Journal of Clinical Practice

Log in or Register to get access to full text downloads.

Remember me or Register

Intrathecal tramadol versus intrathecal fentanyl for visceral pain control during bupivacaine subarachnoid block for open appendicectomy

JM Afolayan, TO Olajumoke, FE Amadasun, NP Edomwonyi


Context: Profound side.effects following intrathecal use of local anesthetics as the sole drugs of choice make spinal anesthesia for open  appendicectomy uncommon.
Aim: The aim of this study was to evaluate the effectiveness of  intra-operative analgesia produced by intrathecal tramadol and fentanyl during bupivacaine spinal anesthesia for open appendicectomy.
Settings and Design: A prospective randomized study was performed.
Materials and Methods: A total of 186 American Society of  Anesthesiologists 1 or 11 patients scheduled for emergency open  appendicectomy were analyzed. Group FB (n = 62) received intrathecal fentanyl 25 µg plus 3 ml of 0.5% hyperbaric bupivacaine, Group SB (n = 62) received 0.5 ml normal saline plus 3 ml of 0.5% hyperbaric  bupivacaine and Group TB (n = 62) received intrathecal tramadol 25 mg plus 3 ml of 0.5% hyperbaric bupivacaine. Visual analog scale scores and frequency of subjective symptoms among patients in the three groups formed the primary outcome measure of this study.
Results: Effective intraoperative sensory block was achieved in 100% of patients in group FB and TB while 29 (46.8%)
patients in group SB had ineffective sensory block (P = 0.0001). The pain free period was significantly longer in patients in
Group FB than Group SB and TB. Mean time for Group FB with regard to first analgesic request was 304.73 ± 67.91 min,
Group SB was 146.59 ± 36.62 and Group TB was 238.39 ± 61.28 min. Incidence of complications were comparable
among the three groups.
Conclusion: This study showed that intrathecal tramadol (25 mg) can safely replace intrathecal fentanyl (25 ƒÊg) in the
management of visceral pain and discomfort during subarachnoid block for appendicectomy.

Key words: Analgesia, appendicectomy, intrathecal opioid, spinal anaesthesia
AJOL African Journals Online