Nigerian Journal of Clinical Practice

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Preoperative and intraoperative continuous use of dexmedetomidine on hyperalgesia after patients’ remifentanil anesthesia

M Yang, J Zhang, F Zhang, H Fang


Objective: Analyze clinical use of dexmedetomidine to relieve prognosis of remifentanil anesthesia recovery and analyze intervention effect.
Materials and Methods: Choose 3600 cases of cerebral functional area operation patients treated in different hospitals during June 2011 and December 2015 for general analysis, group the patients by considering relevant parting of anesthesia recovery by American Society of Anesthesiologists, and divide the patients into dexmedetomidine group and control group according to different use of drugs. The two groups of patients are anesthetized, patients’ anesthesia wake-up time and wake-up success rate are recorded, and effect of two types of anesthesia wake-up way are compared.
Results: There exists no significant statistical difference in wake-up success rate of the two groups of patients, wakeup time has small difference, but anesthesia recovery quality of dexmedetomidine group is higher, which is conducive to physical rehabilitation of patients and minimize the effects of anesthetics on patients.
Conclusion: In clinical surgery, after use of remifentanil anesthesia on patients, use of dexmedetomidine for anesthesia
recovery can minimize adverse effects of drugs on patients and thus is worthy to be effectively promoted in clinics.

Key words: Anesthesia, dexmedetomidine, effect, intervention, preoperative, recovery, remifentanil
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