Serum Vitamin E, Cholesterol and Triglyceride Levels of Nigerian Women with Unexplained Infertility and Recurrent Miscarriage

  • O. S. OLADIMEJI Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria
  • O. A. MAGBAGBEOLA Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria
  • S. S. PETER Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria.
  • T. A. ADEWOLE National Institute of Medicine Research, Yaba, Lagos, Nigeria
  • I. A. AKINWANDE Department of Biochemistry, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria.

Abstract

This study was conducted to examine if there is a relationship between serum lipid and vitamin E levels and unexplained infertility and recurrent miscarriages. Eighty-two (82) healthy Nigerian Women volunteers were recruited for this study. The mean serum cholesterol and triglyceride were slightly higher in the women with unexplained infertility and recurrent miscarriage (177.50 ± 27.80 and 187.54 ± 20.92 mg/l00ml respectively) than the mean value in the fertile women (control) (155.13 ± 32.31 and 162.76 ± 24.70 mg/100ml) respectively. The difference between the sub group were however not statistically significant using the Student t- test. The serum triglycerides concentration in the primary infertility group was (188.88 ± 21.19mg/l00ml} while that of secondary infertility was (185.34 ± 23.77mg/l00ml) and that of recurrent miscarriage was 188.41 ± 17.81mg/l00ml. The difference between these sub groups were of no statistical significance. Mean serum vitamin E concentration in the fertile women (10.36 ± 3.52mg/ml) was found to be insignificantly higher than the observed values in the women with cases of unexplained infertility and recurrent miscarriage (8.97 ± 3.56mg/ml). It was concluded from this study that there is no relationship between recurrent miscarriages and unexplained infertility and the serum lipids and vitamin E levels.

KEY WORDS: Serum, Vitamin E, Cholesterol, Triglyceride, Infertility, Recurrent Miscarriage

[Nig. Jnl Health & Biomedical Sciences Vol.1(2) 2002: 71-75]
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