Effect of Aloe Barbadensis on Rat's Uterine Contractility

  • BO Iranloye Department of Physiology, College of Medicine, University of Lagos.
  • II Olatunji-Bello Department of Physiology, College of Medicine, University of Lagos.
  • AA Ogede Department of Physiology & Biochemistry, Faculty of Health Sciences, University of Ilorin, Nigeria
Keywords: Aloe barbadensis, Uterine contraction, Purgative

Abstract

The present study was undertaken to investigate the effect of the aqueous extract of Aloe barbadensis on the contractility of the uterine stip of a rat. Aqueous extract at final bath concentrations (FBC)1x10-4 mg/ml to 3x101 mg/ml produced a progressive increase in frequency of contraction of the uterine strip. The force of contraction of the uterine strip decreased gradually from FBC of 1x10-4mg/ml to 3x10-3mg/ml. However at higher FBC, Aloe bardadensis showed a progressive increase in force of contraction. We therefore suggest that Aloe barbadensis has some abortifacient effects at high does.

KEY WORDS: Aloe barbadensis, Uterine contraction, Purgative.

Nigerian Journal of Health and Biomedical Sciences Vol.3(2) 2004: 120-122
Published
2004-09-21
Section
Articles

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eISSN: 1595-8272