Nigerian Journal of Natural Products and Medicine
Journal / Nigerian Journal of Natural Products and Medicine / Vol. 1 (1997) / Articles

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DOI:
10.4314/njnpm.v1i1.11792
Keywords:
Sarmentoside-A Strophanthus sarmentosus cardioactivity

Article Details

Issue
Vol. 1 (1997)
Section
Articles
Copyright for articles published in this journal is retained by the journal.

Main Article Content

CARDIO-ACTIVITY OF SARMENTOSIDE-A FROM STROPHANTHUS SARMENTOSUS SEEDS


MO Owonubi
Department of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria
EO Iwalewa
Pharmacology and Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria
M Shok
Department of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria

Abstract

Sarmentoside-A extracted from the seeds of Strophanthus sarmentosus was tested on rabbit heart preparation. Its cardio active property compared favourably with digoxin. Both drugs (Sarmetoside-A and digoxin) increased the force and rate heart contractions; these effects were antagonized by potassium chloride solution.


Key Words: Sarmentoside-A, Strophanthus sarmentosus, cardioactivity


Nig. J. Nat. Prod. And Med. Vol.1 1997: 16-18

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eISSN: 1118-6267
 
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