THE ANALGESIC EFFECTS OF CHENOPODIUM AMBROSIOIDES

  • O.O. Amole Lagos State University College of Medicine, Department of Pharmacology, PMB 21266, Ikeja, Lagos, Nigeria.
  • O.G. Yusuf Lagos State University College of Medicine, Department of Pharmacology, PMB 21266, Ikeja, Lagos, Nigeria

Abstract

Aqueous extract of the leaf of Chenopodium ambrosides, a Nigeria traditional medicinal plant, has been evaluated for its analgesic potential in mice. The analgesic potential of the plant extract was studied using the thermal (hot plate) test. The plant extract was found effective at the dose of 0.4g/kg and 0.8g/kg in elevating pain threshold test. Phytochemical screening of the plant reveals the presence of saponins, alkaloids and volatile oils. The LD50 was calculated to be 4.0g/kg. C. ambrosioides was found to protect mice from the sensation of pain due to thermal stimulus. Key Words: Analgesic effect, Chenopodium, thermal hot plate, mice.

[Nig. J. Nat. Prod. And Med. Vol.6 2002: 36-38]
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