Amyloïdosis, sarcoidosis and systemic lupus erythematosus

  • Amel Rezgui
  • Imene Ben Hassine
  • Monia Karmani
  • Fatma Ben Fredj
  • Chadia Laouani

Abstract

The occurrence of renal and multiple organ Amyloïdosis is currently considered exceptional in the course of systemic lupus erythematosus. We report a case of a concomitant SLE and Amyloïdosis in a 57 year old female patient with hypothyroidism history, who presented with erythema nodosum, fever, arthralgia and sicca syndrome. Biological findings showed an inflammatory syndrome, renal failure, proteinuria (1g / 24h), positive auto antibodies and anti DNA. Lung radiology revealed medistinal lymphadenopathy, pleural nodules, ground glass infiltrates and pleuritis. Bronchial biopsy showed non specific inflammation. The salivary gland biopsy showed amyloïd deposits. This case report reminds us that lupus and Amyloïdosis association, although exceptional remains possible. The occurrence of Lofgren syndrome in this situation make the originality of this report.

Pan African Medical Journal 2016; 24

Author Biographies

Amel Rezgui
Internal Medicine Department, CHU Sahloul, Tunisia
Imene Ben Hassine
Internal Medicine Department, CHU Sahloul, Tunisia
Monia Karmani
Internal Medicine Department, CHU Sahloul, Tunisia
Fatma Ben Fredj
Internal Medicine Department, CHU Sahloul, Tunisia
Chadia Laouani
Internal Medicine Department, CHU Sahloul, Tunisia
Published
2016-08-29
Section
Articles

Journal Identifiers


eISSN: 1937-8688