Kounis syndrome induced by oral intake of aspirin: case report and literature review

  • Abdelkader Jalil El Hangouche
  • Ouiame Lamliki
  • Latifa Oukerraj
  • Taoufiq Dakka
  • Nawal Doghmi
  • Jamila Zarzur
  • Mohammed Cherti
Keywords: Kounis, zavras syndrome, samter´s triad, myocardial infarction, aspirin allergy, coronary spasm

Abstract

The Kounis-Zavras syndrome is defined as the coincidental occurrence of acute coronary events and hypersensitivity reactions following an allergic reaction including a mast-cell degranulation of vasospastic mediators. This report describes a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma also known as Samter-Beer triad combining nasal polyps, asthma, and aspirin allergy leading to vasospasm and myocardial infarction. All physicians should be aware of The Kounis syndrome and always keep that unique clinical entity in mind to recognize it promptly and direct the therapy at suppressing the allergic reaction.

Keywords: Kounis, zavras syndrome, samter´s triad, myocardial infarction, aspirin allergy, coronary spasm

Author Biographies

Abdelkader Jalil El Hangouche
Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco; Exercise Physiology and Autonomic Nervous System Team "EPE-SNA", Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco; Laboratory of Physiology, Faculty of Medicine and Pharmacy of Tangier, Abdelmalek Essaâdi University, Tangier, Morocco
Ouiame Lamliki
Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco
Latifa Oukerraj
Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco
Taoufiq Dakka

Exercise Physiology and Autonomic Nervous System Team "EPE-SNA", Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco

Nawal Doghmi
Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco
Jamila Zarzur
Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco
Mohammed Cherti
Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco
Published
2019-02-11
Section
Articles

Journal Identifiers


eISSN: 1937-8688