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Microbiome Diversity and Gut Health: A Multidimensional Analysis


Sanjay Thorat
Pankaj Nivrutti Pawar
Dhairyasheel Patil
Mahendra M. Alate
Nahed Mohammed Abdelgabaar

Abstract

A complex and dynamic community of bacteria living in the gastrointestinal tract called the human gut microbiome plays a crucial role in preserving gut health and affecting numerous aspects of human physiology. This multifaceted investigation, which considers microbiome composition, immunological function, metabolism, gastrointestinal illnesses, and therapeutic implications, investigates the fundamental link between microbial diversity and gut health. Individual differences in the composition of the gut microbiome, which is home to billions of microbes, can be attributed to dietary habits, genetics, and environmental exposures. Due to the effects it has on digestion, vitamin absorption, and general health, this diversity is essential for gut health. The microbiome also plays a crucial role in the development, tolerance, and control of inflammatory responses of the human immune system. It affects the metabolism of lipids and cholesterol as well as the management of hunger and energy balance. Microbial imbalance, or dysbiosis, has been linked to a number of gastrointestinal conditions, such as inflammatory bowel disease and irritable bowel syndrome. Potential cures for gut health restoration include therapeutic therapies including probiotics, prebiotics, and faecal microbiota transplantation. Furthermore, personalised microbiome-based medicines show promise since they provide tailored solutions to deal with particular microbial imbalances. The gut microbiota is becoming an increasingly important focal point for improving gut health and comprehending its implications for general wellbeing as research develops.


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eISSN: 1812-1659