Bilateral, posterior parietal polymicrogyria as part of speech therapy work-up
Congenital bilateral perisylvian syndrome (CBPS) was traditionally
associated with pseudobulbar palsy, cognitive deficits and epilepsy. However studies have found that the clinical spectrum of CBPS is much broader including patients without epilepsy, but with serious developmental language disorder. Magnetic resonance imaging (MRI) has been associated with either diffuse polymicrogyria around the entire extent of the sylvian fissure or in the posterior aspects of the parietal regions, in which case it is called posterior parietal polymicrogyria. This article discusses the possible embryological origin of these
lesions, the MRI findings using specific protocols and the ability of thinslice MRI 1.5 Tesla units to make the diagnosis of bilateral posterior parietal polymicrogyria in a child with speech pathology.
South African Journal of Radiology Vol. 10 (1) 2006: pp. 25-27