Invasive amoebiasis: circulating antibody levels by latex agglutination test
Sera from 97% of 200 patients with invasive amoebiasis and 15% of 100 general medical patients gave positive results when quantitatively tested with a latex agglutination test. All degrees of agglutination were observed and no correlation was found between latex agglutination results and non-invasive amoebae in the gut. Follow-up sera obtained over a period of 6 months from 8 patients showed reactions of varying intensity. It was concluded that individual variation in antibody production was such that the test could not be used as an index of severity but should simply be read as either positive or negative.