PROMOTING ACCESS TO AFRICAN RESEARCH

Sudan Journal of Medical Sciences

Log in or Register to get access to full text downloads.

Remember me or Register



Expression of Estrogen and Progesterone Receptors among Sudanese Women with Breast Cancer: Immunohistochemical Study

H G Ahmed, S H Safi, A I Shumo, M Abdulrazig

Abstract




Study design: This is a descriptive study to detect the level of Estrogen (ER) and Progesterone (PR) receptors in a
sample of biopsies from Sudanese women with breast cancer presented at Khartoum teaching Hospital
Material and Methods: Forty biopsies from breast cancer patients were examined with immunostaining
using anti-sera to ER and PR as markers to detect receptors.
Results: All the specimens showed the typical histopathologic features of breast cancer. Immunoreactivity testing
revealed positive ER in thirty-six patients (90%) and positive PR in thirty-one patients (77.5%). Of the 36 ER positive
samples, staining intensity was: strong in 20 (55.5 %) moderate in 10 (27.7 %) and weak in 6 (16.7 %). Of the 31 PR
positive samples, 15 (48.4 %) showed strong staining, 7 (22.5 %) moderate and 9 (29.0 %) weak staining
Conclusion: the studied specimens showed high level of positive ER and PR receptors

Sudan Joural of Medical Studies Vol. 2 (1) 2007: pp. 5-6



http://dx.doi.org/10.4314/sjms.v2i1.38458
AJOL African Journals Online