Histological Pattern of Cervical Malignancies in Southwestern Nigeria
AbstractBackground: Malignant diseases of the uterine cervix are typically common among women in the developing countries of the world where they cause a lot of reproductive ill-health and mortality at the prime of age.
Objectives:The aim of this study is to present the histological pattern of cervical malignancies as they present at Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) Ile-Ife between 1990 and 1999
Materials and Methods: The data for the study was collected retrospectively from the surgical daybooks of the histopathology department of the OAUTHC Ile-Ife from January 1990 to December 1999. All cervical biopsies and hysterectomy specimens from which a histopathological diagnosis of malignant tumour of the cervix was made form the subject for this study.
Results: The results revealed 192 cases (45.5%) of cervical malignancies out of the 422 cervical surgical biopsies over the period of study. The age range of the patients was 20 to 89 years with a peak age incidence of 40 49 years. Histopathological study revealed squamous cell carcinoma in 85.4% with a preponderance of Large cell nonkeratinising squamous cell carcinoma in 41.1%, keratinising squamous cell carcinoma 32.3% while micro invasive carcinoma and small cell non keratinising tumours are seen in 1.0% and 9.9% respectively. Adenocarcinoma, adeno- squamous carcinoma, metastatic carcinoma and sarcomas occur in 8.3%, 3.6%, 1.6% and 1.0% respectively.
Conclusion:Squamous cell carcinoma constitutes the main histological type with a high preponderance of large cell non-keratinising squamous cell carcinoma
Key Words: Histological, Pattern, cervical, malignancies, Nigeria.
[Trop J Obstet Gynaecol, 2004;21:118-121]
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