Article Sidebar
Published:
May 27, 2014Keywords:
Article Details
Submission of a manuscript to this journal is a representation that the manuscript has not been published previously and is not under consideration for publication elsewhere.
All authors named in each manuscript would be required to sign a form (to be supplied by the Editor) so that they may retain their copyright in the article but to assign to us (the Publishers) and its licensees in perpetuity, in all forms, formats and media (whether known or created in the future) to (i) publish, reproduce, distribute, display and store the contribution, (ii) translate the contribution into other languages, create adaptations, reprints, include within collections and create summaries, extracts and/or abstracts of the contribution, (iii) create any other derivative works(s) based on the contribution, (iv) to exploit all subsidiary rights in the contribution, (v) the inclusion of electronic links from the contribution to third party material where-ever it may be located, and (vi) license any thrid party to do any or all of the above.
Main Article Content
Factors Associated with Treatment Response to Antidiabetic Agents in Compliant Type 2 Diabetes Mellitus Patients: A Brief Summary of 5-Year Data
Abstract
Purpose: To evaluate the response to diabetic medications and factors influencing drug response in compliant type 2 diabetes mellitus (T2DM) patients.
Methods: A cross-sectional, retrospective study was performed on 100 T2DM patients at the University Malaya Medical Centre (UMMC) who were prescribed with at least one antidiabetic medication between January 2007 and December 2011.
Results: Using data from their medical records, it was determined that both fasting plasma glucose (FPG) and glycated hemoglobin (A1c) levels among all subjects were lower than baseline values. However, the reductions were not significant (p = 0.239 and p = 0.093). Factors that were significantly
associated with the response to diabetic medications, include hypertension (p = 0.011), sulfonylureas (p = 0.041), beta-blockers (p = 0.005), and baseline A1c levels (p < 0.001).
Conclusion: Treatment of T2DM can be further optimized to ensure that diabetes is well-controlled.
Keywords: Treatment response; Antidiabetics; Type 2 Diabetes Mellitus, Hypertension, Beta-blocker.
