Antisecretory and analgesic activities of <i>Terminalia bellerica</i>

Abstract

This study describes the antisecretory and analgesic activities of the crude extract of Terminalia bellerica (Tb.Cr). T. bellerica extract inhibited the castor oil-induced intestinal fluid secretion in mice at the dose range of 300 - 1000 mg/kg. The extract also dose-dependently (50 - 100 mg/kg) reduced the
numbers of acetic acid-mediated writhes in mice. These results indicate that T. bellerica exhibit antisecretory and anti-nociceptive effects, hence justifying its medicinal use in diarrhea and pain.