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A 5-year review of research ethics applications in a tertiary health and educational institution in Nigeria

Dennis Amajuoyi Ndububa
Akinjide Olurotimi Ogundokun
Oluwagbemiga Oluwole Ayoola
Adebanjo Babalola Adeyemi
Rahman Ayodele Bolarinwa
Taiwo Olumuyiwa Ogundipe
Abdulkadir Ayo Salako
Aaron Oladiipo Aboderin
Olusegun Temitope Afolabi
Anthony Taiwo Adenekan
Ige Oluwatosin Taiwo
Oluwabanke Gold Akanbi


Background: African contribution to global research output is said to be low. Poor funding and poor skills in grant writing have
been suggested as important factors for this situation.

Objectives: Applications for research ethics clearance in a hospital were reviewed to have an overview of the planned studies
and the proportion of them that attracted national and international funding.

Methods: A review of all applications for ethical clearance received by the institutional review board of a university teaching
hospital at Ile-Ife, Nigeria, from 2016 to 2020. They were analysed according to study nature, scope, purpose, and sponsorship
using descriptive statistics presented as frequency tables and charts.

Results: A total of 878 applications were reviewed. There were 803 (91.5%) applications for local, 45 (5.1%) for national multicentre,
and 30 (3.4%) for international multicentre studies. Applications for medical fellowship were 352 (40.0%) while 208
(23.8%) were from academic staff for non-degree research. There were 610 (69.5%) applications for self-sponsored studies.
Only 18 (2.0%) and 26 (3.0%) received sponsorship from national and international donor agencies, respectively.

Conclusions: Local studies formed the bulk of the submissions for ethics clearance. National and international donor funding
of research is abysmally low in this Nigerian tertiary institution studied.

Keywords: Research ethics applications; study sponsorship.

Journal Identifiers

eISSN: 1729-0503
print ISSN: 1680-6905