Antimicrobial activity of leaf extracts of Ocimum gratissimum on selected diarrhoea causing bacteria in southwestern Nigeria

  • T T Adebolu Department of Microbiology, Federal University of Technology, Akure, Ondo State, Nigeria.
  • Salau Abiola Oladimeji Drug Research Unit, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
Keywords: Antibacterial activity, Ocimum gratissimum, diarrhea


The antibacterial activity of different extracts from the leaves of Ocimum gratissimum was tested against Staphylococcus aureus, Escherichia coli, Salmonella typhi and Salmonella typhimurium, pathogenic bacteria that cause diarrhea. These extracts evaluated include cold water extract (CWE), hot water extract (HWE) and steam distillation extract (SDE). Only SDE has inhibitory effects on the selected bacteria and the minimum inhibitory concentration (MIC) ranged from 0.1% for S. aureus to 0.01% for E. coli and S. typhimurium, and 0.001% for S. typhi.

African Journal of Biotechnology Vol. 4 (7), pp. 682-684, 2005

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eISSN: 1684-5315