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African Journal of Biotechnology

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Phytochemical analysis and antimicrobial screening of crude extracts from the leaves, stem bark and root bark of Ekebergia senegalensis A. Juss

IG Ndukwe, JD Habila, IA Bello, EO Adeleye

Abstract


The leaves, stem bark and root bark of Ekebergia senegalensis, which has some traditional medicinal applications were investigated. Phytochemical analysis gave positive results for carbohydrates, glycosides, saponins, tannins and alkaloids. The crude methanol extracts showed growth inhibitory effects on Salmonella typhi, Pseudomonas, Klebsiella, Bacillus subtilis, Escherichia coli and Staphylococcus aureus. The minimum inhibitory concentration (MIC) of these extracts on the bacteria
is 0.125 x 103 mg/ml for the methanol extracts. The minimum bactericidal concentration (MBC) determination showed that a concentration of 0.03125 x 103 mg/ml of the methanol extract of the leaves could completely kill S. typhi. The petroleum spirit extract did not show marked antimicrobial activity.



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