PROMOTING ACCESS TO AFRICAN RESEARCH

African Journal of Biomedical Research

Log in or Register to get access to full text downloads.

Remember me or Register



Ferulic acid ester from the stem bark of Acacia ataxacantha

A.A. Ahmadu, A. Agunu, B.A. Lawal

Abstract


From the chloroform extract of the stem bark of Acacia ataxacantha, a ferrulic acid derivative identified as n-tetradecanyl-3-methoxy-4-hydroxy –trans-cinnamate (tetradecanyl ferulate) compound 2 was isolated for the first time from this plant alongside the triterpene lupenol. The structure of compound 2 was confirmed using NMR and MS and is reported here for the first time. Primary activity of the isolated compound against a panel of disease related protein kinases reveal the compound to be in-active.

Keywords: Acacia ataxacantha, tetradecanyl ferrulate, protein kinase

Afr. J. Biomed. Res. Vol. 22 (May, 2019); 214- 217



AJOL African Journals Online