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Application of Conformational Space Search in Drug Action

MU Adikwu, KC Ofokansi

Abstract


The role of conformational space in drug action is presented. Two examples of molecules in different therapeutic groups are presented. Conformational space search will lead to isolating the exact conformation with the desired medicinal properties. Many conformations of a plant isolate may exist which are active, weakly active or inactive.

Key Words: Conformational, Space, Drug Action

Bio-Research Vol.1(2) 2003: 69-76



http://dx.doi.org/10.4314/br.v1i2.28530
AJOL African Journals Online