Application of Conformational Space Search in Drug Action

  • MU Adikwu Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria
  • KC Ofokansi Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria
Keywords: Conformational, Space, Drug Action

Abstract

The role of conformational space in drug action is presented. Two examples of molecules in different therapeutic groups are presented. Conformational space search will lead to isolating the exact conformation with the desired medicinal properties. Many conformations of a plant isolate may exist which are active, weakly active or inactive.

Key Words: Conformational, Space, Drug Action

Bio-Research Vol.1(2) 2003: 69-76
Published
2004-04-28
Section
Articles

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print ISSN: 1596-7409