Inhibition of Gastric Erosion Formations in Rats by Adenosine, 5 /-Adenosine Monophosphate and 5 /- Adenosine Diphosphate

  • CA Anosike
  • CI Ezekwe
  • OFC Nwodo
Keywords: Adenosine, AMP, ADP, Anti-ulcer, Antidote, Gastric erosion

Abstract



Gastric erosions were induced in rats with indomethacin, 5-hydoxytryptamine (5-HT) or reserpine. Three adenine compounds adenosine, adenosine, 5 /-adenosine monophosphate (AMP) and 5 /- adenosine diphosphate (ADP) were found to protect against the erosion formations. Both 5-HT and reserpine caused untimely deaths of some of the control animals. Also the adenine compounds prevented the untimely deaths caused by the two ulcerogenes.

Keywords: Adenosine, AMP, ADP, Anti-ulcer, Antidote, Gastric erosion

Bio-Research Vol. 6 (1) 2008: pp. 346-347
Published
2009-01-06
Section
Articles

Journal Identifiers


eISSN: 2705-3822
print ISSN: 1596-7409