In-Vitro antibacterial activity of bioactive plant extracts against methicillin-resistant strains of staphylococcus aureus
Abstract
Methanol extract of leaves of five different Nigerian plants were tested for activity against three drug resistant strains of Staphylococcus aureus by the agar well diffusion and broth microdilution techniques. The S. aureus strains were composed of two clinical isolates and one reference strain. Promising antimicrobial activity was displayed by three of the five plants tested. Minimum inhibitory concentration (MIC) of the extracts ranged from 25 mg/ml to 100 mg/ml. The clinical isolates had comparable level of sensitivity to the three most active extracts. Both were also more susceptible to the extracts than the reference strain. Phytochemical analyses showed that secondary plant constituents were present in varied concentrations in all the extracts.Bio-Research journal is an open access journal, which means all its content is freely available without charge to the user or his/her institution.
You are free to share (that is, copy and redistribute the material in any medium or format) as long as you follow these licence terms:
Attribution (by)
You must give appropriate credit, provide a link to the license.
Non Commercial (nc)
You can copy, distribute, display, perform, and use this material for any purpose other than commercially (unless you get permission first). Non Commercial means not primarily intended for or directed towards commercial advantage or monetary compensation.
No Derivatives (nd)
If you remix, transform, or build upon the material, you may not distribute the modified material. But note that simply changing the format does not create a derivative.
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the licence permits.
Notices
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
