Solid State Synthesis, Characterization and Anti-Microbial Studies of some Transition Metal Complexes of a Schiff Base Ligand Derived from Benzophenone and Glycine

  • Mukhtar A. Kurawa
  • Jamilu Jaafar
Keywords: Anti-microbial activities, Benzophenone, Glycine, Cu(II), Co(II), Mn(II), Solid State Synthesis

Abstract

Schiff base was synthesized by mixing benzophenone and glycine mechanochemically. Its corresponding complexesof Cu, Co and Mn were synthesized by grinding metal (II)carbonates. The synthesized compound were characterized by elemental analysis, infrared spectroscopy, .melting/decomposition temperature determination and conductivity measurements .The infrared spectroscopic analysis of the ligand shows a peak at 1624.12cm-1 confirm the presence of azomethane while the shift to1600 cm-1,1590 cm-1, 1590 cm-1 in Mn, Cu, Co complexes respectively confirmed bond formation from azo-group to metal. The melting point temperature of the ligand at 174.200C show that it is stable at low temperature while the decomposition temperature of Mn, Cu, Co complexes at 2000C,2300C,217.120C shows that they are stable .conductivity measurement shows that the complexes were found to be non-electrolytic as compared with the theoretical values.The ligand and its respective complexesshowedAntimicrobial activities against some bacteria and fungi at high concentrations (1000 μg/disc and 500 μg/disc) respectively while some showed no activity at all concentrations. However, Co complex shows significant activity against all the species at low concentration (250 μ/disc).

Published
2021-07-05
Section
Articles

Journal Identifiers


eISSN: 2384-6028
print ISSN: 2276-707X