Iron and Cancer: A Review

  • PM Ofordile Department of Medical Laboratory Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu Nigeria
  • PU Achukwu Department of Medical Laboratory Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu Nigeria
  • AA Ngokere Morbid Anatomy, College of Medicine, University of Nigeria, Enugu Campus, Enugu Nigeria
  • AA Ofodile Radiation Medicine, College of Medicine, University of Nigeria, Enugu Campus, Enugu Nigeria.

Abstract

Iron overload constitutes a major health problem worldwide, and deserves attention. This review covers a few of the proliferating literature ranging from mechanisms of its carcinogenesis, iron-withholding defense system and its attendant risks, to suggestions of prevention and control.

Key Words: Iron, Cancer, Peroxyl radicals, haemochromatosis, neoplastic cells.

(J College Med: 2003 8(1): 16-19)
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