Comparative effects of Potash Sodium Chloride (PSC) mixture and honey on incisional wound healing in albino rats

Abstract

Honey (Mellifica sp) is produced by Apis mellifera africana, widely consumed without prescription or restriction, and has been shown to possess wound healing and antitusive properties. Comparative study of the effects of honey paste and Potash Sodium Chloride (PSC) mixture on the healing of incisional wound on albino wistar rats was undertaken. Fresh and open incisional wound was inflicted on healthy rats, and was treated with honey paste and Potash Sodium Chloride (PSC) mixture comparatively. Results showed that PSC mixture demonstrated faster wound healing than honey because the WBC and platelets in test groups increased by 20% while the lymphocytes and eosinophil decreased by 48% and 96.9% respectively. The duration of healing was also faster in animals treated with PSC mixture (10.9 ± 3.9days) than rats treated with honey paste (13.4 ± 3.5 days). We conclude that although honey paste may have effect on wound healing, PSC mixture has proved to be more efficacious and faster duration of healing.

Keywords: incisional wound healing, honey, potash.