The effects of Vitamin A on tear break-up time of young adults

  • FO Iwuagwu
  • GC Agu
  • YC Azuamah
  • VU Okolie


This study was carried out to determine the effect of increased intake of vitamin A on Tear break-up time (TBUT). One hundred asymptomatic healthy young adults; 50 males and 50 females all within the ages of 18 and 30 years were used for this study. Results showed a range of 13-28 seconds and a mean TBUT of 19.12 seconds before the administration of vitamin A. After 20 days of a seven-day administration of vitamin A, the range becomes 16-31 seconds and a mean TBUT of 21.79 seconds. This showed an increase of 2.67 seconds in the mean TBUT. Measuring the correlation between the observations using the Spear man rank- order correlation coefficient at 0.05 level of significance, there was a significant improvement in TBUT after the administration of vitamin A.

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eISSN: 0795-0039
print ISSN: 0795-0039