PROMOTING ACCESS TO AFRICAN RESEARCH

Journal of Pharmaceutical and Allied Sciences

Log in or Register to get access to full text downloads.

Remember me or Register



DOWNLOAD FULL TEXT Open Access  DOWNLOAD FULL TEXT Subscription or Fee Access

Postharvest UV - C treatment positively affects the bioactive components, antioxidant, antidiabetic and inhibition of Fe2+ - induced lipid peroxidation properties of Gongronema latifolia leaf extracts

O Adetuyi Foluso, A Demehin Adebisi

Abstract


This research work is to investigate the effect of radiating Gongronema latifolium leaves with UV-C light on the bioactive component, antioxidant, antidiabetic and Fe2+ induced lipid peroxidative inhibitory capacity of the leaves. The leaves were freshly harvested and divided into 3 parts; one part was treated with UV-C lamp at 210 nm for 10 minutes (UV-C 10), the second part for 20 minutes (UV-C 20) while the last part was not treated. The aqueous extracts of G. latifolium were used for the analysis. The UV-C 20 sample had a higher level of total phenolics (6.10 mgGAE/g) and total flavonoids (0.64 mgQE/g). However, the untreated sample showed a significantly (p ˂ 0.05) higher value of ascorbic acid than the treated samples. There was increase in the scavenging and inhibiting abilities of G. latifolium when irradiated with UV-C. The UV-C 20 sample exhibited a higher and significant (p ˂ 0.05) DPPH scavenging and metal chelating abilities as well as higher inhibitory effect on α-amylase, α-glucosidase enzyme and Fe2+ induced lipid peroxidation in vitro. The UV-C irradiated leaves could be used therapeutically for the correction of stress induced diseases.

Keywords: Gongronema latifolium, UV-C, phenolic, ascorbic acid, total flavonoid, DPPH scavenging activity, α-amylase, α-glucosidase enzyme




AJOL African Journals Online