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A rare case of pituitary chromophobe carcinoma in a dog: Clinical, tomographic and histopathological findings

M. Longo
D. Binanti
P.G. Zagarella
F. Iocca
D. De Zani
G. Ravasio
M. Di Giancamillo
D.D. Zani


A 9 year old male mixed-breed dog was presented for progressive aggressiveness towards the owner. The neurological evaluation was consistent with a forebrain  syndrome. Magnetic Resonance Imaging (MRI) of the brain revealed enlargement of the third ventricle and presence of a large spheroidal neoplasm in the sellar/parasellar region suggestive of a pituitary macroadenoma. On the owner request, the dog was euthnized. Histopathological examination revealed the presence of a pituitary  chromophobe carcinoma. To the author’s knowledge, pituitary carcinomas have been rarely described in dogs, especially the chromophobe subtype.

Keywords: Brain, Chromophobe carcinoma, Histology, Pituitary neoplasm, Tumour.

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eISSN: 2218-6050
print ISSN: 2226-4485