Pan African Medical Journal

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Clinical case: giant solitary neurofibroma of the thigh

Mamoudou Sawadogo, Salam Ouedraogo, Alassane Drave, Souleymane Ouedraogo, Hamado Kafando, Sayouba Tinto, Anatole Jean Innocent Ouedraogo, Alexandre Stanislas Korsaga, Mohamed Tall, Songahir Christophe Da


The solitary neurofibroma, a benign ectodermal tumor reaching the nerve sheaths, is very rare both in its frequency and its location. Its diagnosis is histo-immunological and its treatment, surgical, consists of a complete resection of the mass due to a degenerative risk tumor. The authors report the case of a 36-year-old patient, admitted for a large tumor of the anterior aspect of the right thigh. Ultrasound and CT revealed the presence of a soft tissue tumor measuring 28 x 15 cm. The resection was performed without damage to the adjacent noble elements. The tumor weighed 7 kg. The histology found a neurofibroma. Benign tumors of the nerve sheath are rare. The neurofibroma is a benign tumor, which can occur in two forms: solitary in young adults or multiple in the context of a Recklinghausen disease. The majority of cases of giant neurofibromatous tumors reported, were almost always isolated localization. TDM or echo-guided biopsy is the only way to confirm preoperative histological diagnosis. The treatment is surgical. However, the tumor infiltrates the fasciculi of the nerve along its course, which could make its resection difficult and dangerous. Thigh localization of the neurofibroma is rare. Complete excision with negative margins is the treatment of choice. In the case reported, one year after surgery, the patient was in good general condition with normal locomotor function.

AJOL African Journals Online