Isolation, Characterization and X-ray Structure Determination of the Schiff Base Ligand: 5-Methyl-2-phenyl-4-[phenyl-(4-phenyl-thiazol-2-ylamino)- methylene]-2,4-dihydro-pyrazol-3-one
The structure of the amine tautomer of the new Schiff base derived from 4-benzoyl-5-methyl-2-phenyl-2,4-dihydro-pyrazol- 3-one (2) and 4-phenyl-thiazol-2-ylamine (3) was confirmed by means of single crystal X-ray diffraction. The title compound (4) was synthesized and crystals were grown from a mixture of dichloromethane and n-hexane (1:3). Single crystal X-ray diffraction analysis show that the structure is primarily stabilized by strong intramolecular N3–H3A···O1 hydrogen bonds [N3–H3A = 0.883(19) Å, H3A···O1=1.925(18) Å, N3···O1=2.6901(13) Å, with an angle for N3–H3A···O1=144.1(17) °] and this leads to the formation of a pseudo nine-membered hydrogen bonded pattern. Elemental analysis, FTIR andNMRanalyses have been employed to characterize the crystal.
KEYWORDS Pyrazolone, thiazole, Schiff base, tautomer, X-ray structure.
PDF and Supp files attached
Copyright for articles published in this journal is retained by the journal.
SAJChem applies the Creative Commons Attribution (CC BY) license to manuscripts we publish. This license was developed to facilitate open access – namely, free immediate access to, and unrestricted reuse of, original works of all types. Under this license, authors agree to make articles legally available for reuse, without permission or fees, for virtually any purpose. Anyone may copy, distribute or reuse these articles, as long as the author and original source are properly cited.